The AIT will be in charge of the coordination of the project. In addition, it will provide the bacterial antigens for the aptamer-like structure selection process, develop the customised DNA-origami software and design the DNA scaffold of the MORO. The assembly and functionality of the MORO will be evaluated in cooperation with the partners.
The UF will be in charge of understanding the archaellum subunit interactions and modelling the mechanism of motor rotation in collaboration with the ICL partner and will deliver the obtained results to the other work packages.
The AU is participating in creation of the 4-models for visualisation by electron cryo-tomography (WP3). Furthermore, AU will test the functionality of the developed DNA molecules by using artificial membrane systems enabling the precise measurement of their activity (WP4).
PureB will carry out the selection of proprietary chemically modified aptamers towards chosen pathogen's targets for use in the project.